Normal Dose|Renal Impairment|Hemodialysis
___________________________________________________________
| Indication | Dose | Frequency | Cost |
| Uncomplicated urinary tract infections | 1 gram | Q6 hours | $15.48/day |
| Complicated urinary tract infections | 150-200 mg/kg/day | divide dose Q4-6 hours | |
| Septicemia | 200-300 mg/kg/day | divide dose Q4-6 hours | |
| Respiratory tract infections | 200-300 mg/kg/day | divide dose Q4-6 hours | |
| Skin and soft-tissue infections | 200-300 mg/kg/day | divide dose Q4-6 hours | |
| Intra-abdominal infections | 200-300 mg/kg/day | divide dose Q4-6 hours | |
| Genitourinary infections | 200-300 mg/kg/day | divide dose q4-6 hours |
| Creatinine Clearance | Dosage and Frequency |
| Crcl 30-60 ml/min | 3 gram loading dose followed by a maintenance dose of 2 grams Q4 hours |
| Crcl 10-30 ml/min | 3 gram loading dose followed by a maintenance dose of 2 grams Q8 hours |
| Crcl <10 ml/min | 3 gram loading dose followed by a maintenance dose of 2 grams Q12 hours |
| Dose | Frequency |
| 2 grams | Q12 hours and an additional 3 grams after each dialysis period |