Normal Dose|Renal Impairment|Hemodialysis
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| Indication | Dose | Frequency | Cost |
| Uncomplicated urinary tract infections | 6-8 grams/day | divide dose Q6-12 hours | $42.88/day |
| Complicated urinary tract infections | 8-16 grams/day | divide dose Q6-8 hours | $85.76/day |
| Community acquired pneumonia | 6-8 grams/day | divide dose Q6-12 hours | $42.88/day |
| Septicemia | 12-18 grams/day | divide dose Q4-6 hours | $96.48/day |
| Nosocomial pneumonia | 12-18 grams/day | divide dose Q4-6 hours | $96.48/day |
| Intra-abdominal infections | 12-18 grams/day | divide dose Q4-6 hours | $96.48/day |
| Aerobic and anaerobic gynecologic infections | 12-18 grams/day | divide dose Q4-6 hours | $96.48/day |
| Skin and skin structure infections | 12-18 grams/day | divide dose Q4-6 hours | $96.48/day |
| Febrile granulocytopenic -empiric therapy | 250-300 mg/kg/day | given in 4 or 6 divided doses | |
| Acute exacerbations of bronchopulmonary Ps.aeruginosa infections in cystic fibrosis | 300-600 mg/kg/day | divide dose Q4-6 hours with an aminoglycoside |
| Indication | Creatinine Clearance | Creatinine Clearance |
| 20-40 ml/min | <20 ml/min | |
| Uncomplicated urinary tract infections | no adjustment needed | 3 grams Q12 hours |
| Complicated urinary tract infections | 3 grams Q8 hours | 3 grams Q12 hours |
| Serious systemic infections | 4 grams Q8 hours | 4 grams Q12 hours |
| Dose | Frequency |
| 2 grams | Q8 hours during hemodialysis and 1 gram additional dose should be given after each dialysis |