Normal Dose|Renal Impairment|Hemodialysis
__________________________________________________________
| Indication | Dose | Frequency | Cost |
| Exacerbation of chronic bronchitis | 400 mg | Q12 hours for 10 days | |
| Community acquired pneumonia | 400 mg | Q12 hours for 10 days | |
| Cervicitis/urethritis due to C. trachomatis | 300 mg | Q12 hours for 7 days | |
| Cervicitis/urethritis due to C. trachomatis and N. gonorrhoeae | 300 mg | Q12 hours for 7 days | |
| Acute pelvic inflammatory disease | 400 mg | Q12 hours for 10-14 days | |
| Uncomplicated skin and skin structure infections | 400 mg | Q12 hours for 10 days | |
| Uncomplicated cystitis due to E.coli or K. pneumoniae | 200 mg | Q12 hours for 3 days | |
| Uncomplicated cystitis due to other organisms | 200 mg | Q12 hours for 7 days | |
| Complicated urinary tract infections | 200 mg | Q12 hours for 10 days | |
| Prostatitis | 300 mg | Q12 hours for 6 weeks |
| Creatinine Clearance | Dose and Frequency |
| Crcl 20 to 50 ml/min | usual dose Q24 hours |
| Crcl <20 ml/min | 1/2 usual recommended dose Q24 hours |
| Dose | Frequency |
| 200 mg loading followed by 100 mg | Q24 hours; additional supplemental doses of the drug are unnecessay following each hemodialysis; however , a single 100 mg supplemental oral dose of the drug be given after the first hemodialysis procedure |