Normal Dose|Renal Impairment|Hemodialysis
__________________________________________
| Indication | Dose | Frequency | Cost |
| Uncomplicated urinary tract infections | 1.5-2 grams | Q6 hours | $35.76/day |
| Complicated urinary tract infections | 3 grams | Q 6 hours | $71.52/day |
| Lower respiratory tract infections | 3 grams
4 grams |
Q4 hours
Q6 hours |
$107.28/day
$71.52/day |
| Intra-abdominal infections | 3 grams
4 grams |
Q4 hours
Q6 hours |
$107.28/day
$71.52/day |
| Gynecologic infections | 3 grams
4 grams |
Q4 hours
Q 6 hours |
$107.28/day
$71.52/day |
| Skin and skin structure infections | 3 grams
4 grams |
Q4 hours
Q6 hours |
$107.28/day
$71.52/day |
| Septicemia | 3 grams
4 grams |
Q4 hours
Q6 hours |
$107.28/day
$71.52/day |
| Life-threatening infections | 4 grams | Q4 hours | $107.28/day |
| Severe gram-negative infections including Pseudomonas aeruginosa | 2-4 grams | Q4-6 hours with an aminoglycoside | $53.64-$107.28/day |
| Febrile granulocytopenic cancer patients | 3-5 grams | Q4-6 hours with an aminoglycoside | $107.28-$160.92/day |
| Indication | Creatinine Clearance | Creatinine Clearance |
| 10-30 ml/min | <10 ml/min | |
| Uncomplicated urinary tract infections | 1.5 grams Q8 hours | 1.5 grams Q8 hours |
| Complicated urinary tract infections | 1.5 grams Q6 hours | 1.5 grams Q8 hours |
| Serious systemic infections | 3 grams Q8 hours | 2 grams Q8 hours |
| Life-threatening infections | 3 grams Q6 hours | 2 grams Q6 hours |
| Dose | Frequency |
| 3-4 grams | after each hemodialysis procedure, and then every 12 hours |