Normal Dose|Renal Impairment|Hemodialysis
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| Indication | Dose | Frequency | Cost |
| Anaerobic infections | 15 mg/kg initial dose followed by 7.5 mg/kg (inj) | Q6 hours | |
| Amebic liver abscess | 500-750 mg (po) | TID for 5-10 days | $1.00/day |
| Amebic dysentery | 750 mg (po) | TID for 5-10 days | $1.00/day |
| Anaerobic bacterial infections | 7.5 mg/kg (po) | Q6 hours | $1.00/day |
| Bacterial vaginosis- nonpregnant women | 500 mg | BID for 7days | |
| Bacterial vaginosis- pregnant women | 250 mg | TID for 7 days | |
| Giardiasis | 250 mg | TID for 5 days | |
| Pseudomembranous colitis | 500 mg | TID | |
| Trichomoniasis | 250 mg | TID for 7 days |
| Creatinine Clearance | Dose and Frequency |
| Crcl >10ml/min | no dosage adjustment is necessary |
| Crcl <10 ml/min | 50% of the normal dose at the usual intervals |
| Dose and Frequency |
| Maintenance dose to be given to patients following hemodialysis |