MEROPENEM

Normal Dose|Renal Impairment|Hemodialysis

Index

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Normal Dose

 

Indication Dose Frequency Cost
Febrile Neutropenia 1 gram Q8 hours $126.87/day
Complicated appendicitis and peritonitis 1 gram Q8 hours $126.87/day
Meningitis 2 grams Q8 hours $253.74/day
Skin and soft tissue infections 500 mg Q8 hours $63.42/day
Urinary tract infections 500 mg Q12 hours $42.28/day


Renal Impairment

 

Creatinine Clearance Dose and Frequency
Crcl >50 ml /min no adjustment
Crcl 26 to 50 ml/min 1 gram Q12 hours
Crcl 10 to 25 ml/min 500 mg Q12 hours
Crcl <10 ml/min 500 mg Q24 hours


Hemodialysis

 

Dose and Frequency

Meropenem is removed during hemodialysis, and an additional dose to be given following dialysis

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