Normal Dose|Renal Impairment|Hemodialysis
_________________________________________________________
| Indication | Dose | Frequency | Cost |
| Acute bacterial exacerbation of chronic bronchitis | 400 mg | Q24 hours for 10 days | $5.77/day |
| Uncomplicated cystitis caused by K. pneumoniae, P. mirabilis, or S. saprophyticus | 400 mg | Q24 hours for 10 days | $5.77/day |
| Uncomplicated cystitis in females caused by E.coli | 400 mg | Q24 hours for 3 days | $5.77/day |
| Complicated urinary tract infections | 400 mg | Q24 hours for 14 days | $5.77/day |
| Creatinine Clearance | Dose and Frequency |
| Crcl >40 ml/min | usual dose and dosing interval |
| Crcl 10-40 ml/min | 400 mg initial dose followed by a maintenance dose of 200 mg Q24 hours |
| Dose | Frequency |
| 400 mg initial dose followed by 200 mg | Q24 hours |