Normal Dose|Renal Impairment|Hemodialysis
_________________________________________________________________
| Indication | Dose | Frequency | Cost |
| Acute bacterial exacerbation of chronic bronchitis | 500 mg | Q24 hours for 7 days | $6.31/day(po)
$32.97/day(inj) |
| Community-acquired pneumonia | 500 mg | Q24 hours for 7-14 days | |
| Acute maxillary sinusitis | 500 mg | Q24 hours for 10-14 days | |
| Complicated skin and skin structure infections | 750 mg | Q24 hours for 7-14 days | $7.65/day(po) |
| Uncomplicated skin and skin structure infections | 500 mg | Q24 hours for 7-10 days | |
| Complicated urinary tract infections | 250 mg | Q24 hours for 10 days | $5.41/day(po)
$16.48/day(inj) |
| Uncomplicated urinary tract infections | 250 mg | Q24 hours for 3 days | |
| Acute pyelonephritis | 250 mg | Q24 hours for 10 days |
| Creatinine Clearance | Dose and Frequency |
| Crcl 50-80 ml/min | usual dose and dosing interval |
| Crcl 20-49 ml/min | 500 mg initial dose followed by 250 mg Q24 hours |
| Crcl 10-19 ml/min | 500 mg initial dose followed by 250 mg Q48 hours |
| Dose | Frequency |
| 500 mg | 250 mg Q48 hours |