GENTAMICIN

Normal Dose|Renal Impairment|Hemodialysis

Index

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Normal Dose

 

Indication Dose Frequency Cost
Bacterial infections- usual dose 3 mg/kg/day divide dose Q8 hours  
Pulmonary infections caused by Haemophilus influenzae and Staphylococcus aureus in patients with cystic fibrosis 3 mg/kg/day divide dose Q8 hours given with ticarcillin-clavulanate or nafcillin  


Renal Impairment

 

Creatinine Clearance Dose and Frequency
Crcl >50 ml/min 60%-90% of the normal dose Q8-12 hours
Crcl 10-50 ml/min 30%-70 % of the dose Q12 hours
Crcl <10 ml/min 20%-30 % of the dose Q24-48 hours


Hemodialysis

 

Dose Frequency
1 to 1.7 mg/kg to be given at the end of each dialysis

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