Normal Dose|Renal Impairment|Hemodialysis
____________________________________________________________
Indication | Dose | Frequency | Cost |
Bacterial infections- usual dose | 3 mg/kg/day | divide dose Q8 hours | |
Pulmonary infections caused by Haemophilus influenzae and Staphylococcus aureus in patients with cystic fibrosis | 3 mg/kg/day | divide dose Q8 hours given with ticarcillin-clavulanate or nafcillin |
Creatinine Clearance | Dose and Frequency |
Crcl >50 ml/min | 60%-90% of the normal dose Q8-12 hours |
Crcl 10-50 ml/min | 30%-70 % of the dose Q12 hours |
Crcl <10 ml/min | 20%-30 % of the dose Q24-48 hours |
Dose | Frequency |
1 to 1.7 mg/kg | to be given at the end of each dialysis |