Normal Dose|Renal Impairment|Hemodialysis
_______________________________________________________________
| Indication | Dose | Frequency | Cost |
| Serious infections | 150-300 mg (po) | Q6 hours | $1.76-$3.52/day |
| More severe infections | 300-450 mg (po) | Q6 hours | $3.52-$5.28/day |
| Serious infections due to aerobic gram-positive cocci and the more sensitive anaerobes | 600-1200 mg (inj)/day | divide dose in 2-4 equal doses | $8.34-$16.68/day |
| More severe infections due to B. fragilis, Peptococcus sp. or Clostridium sp. other than C. perfringens | 1.2-2.7 grams (inj) /day | divide dose in 2-4 equal doses | $16.68-$30.54/day |
| Dose and Frequency |
| No dosage adjustment is necessary |
| Dose and Frequency |
| No dose adjustment is necessary |