Normal Dose|Renal Impairment|Hemodialysis
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| Indication | Dose | Fequency | Cost |
| Acute bacterial exacerbation of chronic bronchitis | 250 mg | BID | $5.88/day |
| Secondary bacterial infections of acute bronchitis | 250 mg | BID | $5.88/day |
| More severe infections or infections caused by less susceptible organisms | 500 mg | BID | $11.76/day |
| Early lyme disease | 500 mg | BID for 20 days | $11.76/day |
| Pharyngitis , tonsillitis or acute bacterial maxillary sinusitis | 250 mg | BID for 10 days | $5.88/day |
| Cystic fibrosis to suppress the growth of S aureus and H influenzae in the respiratory tract | 250-500 mg | Q12 hours | $11.76/day |
| Skin and skin structure infections | 250 mg | BID for 10 days | $5.88/day |
| More severe skin infections or for infections caused by less susceptible organisms | 500 mg | BID | $11.76/day |
| Uncomplicated urinary tract infections | 125 mg | BID for 7-10 days | $2.94/day |
| Creatinine Clearance | Dose and Frequency |
| Crcl >50 ml/min | 250 mg to 500 mg Q8 hours |
| Crcl 49 to 30 ml/min | 250 mg to 500 mg Q12 hours |
| Crcl 29 to 10 ml/min | 250 mg to 500 mg Q24 hours |
| Crcl <10 ml/min | 250 mg to 500 mg Q48 hours |
| Dose | Frequency |
| 250 - 500 mg | to be given after each dialysis |