Normal Dose|Renal Impairment|Hemodialysis
_____________________________________________________________
| Indication | Dose | Frequency | Cost |
| Bone and joint infections | 1.5 grams | Q8 hours | $17.58/day |
| Life -threatening infections or infections due to less susceptible organisms | 1.5 grams | Q6 hours | $23.44/day |
| Bacterial meningitis | 3 grams(not to exceed) | Q8 hours | $35.16/day |
| Uncomplicated pneumonia | 750 mg | Q8 hours | $8.82/day |
| Severe or complicated pneumonia | 1.5 grams | Q8 hours | $17.58/day |
| Skin and skin structure infections | 750 mg | Q8 hours for 5-10 days | $8.82/day |
| Severe or complicated skin and skin structure infections | 1.5 grams | Q8 hours | $17.58/day |
| Uncomplicated urinary tract infections | 750 mg | Q8 hours for 5-10 days | $8.82/day |
| Severe or complicated urinary tract infections | 1.5 grams | Q8 hours | $17.58/day |
| Creatinine Clearance | Dose and Frequency |
| Crcl >20 ml/min | 750 mg- 1.5 grams Q8 hours |
| Crcl 10-20 ml/min | 750 mg Q12 hours |
| Crcl <10 ml/min | 750 mg Q24 hours |
| Dose | Frequency |
| Supplemental dose | to be given after each dialysis |