Normal Dose|Renal Impairment|Hemodialysis
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Indication | Dose | Frequency | Cost |
Uncomplicated urinary tract infections | 250 mg | Q12 hours | $7.08/day |
Complicated urinary tract infections | 500 mg | Q8-12 hours | $10.62/day |
Uncomplicated pneumonia | 500 mg | Q8 hours | $10.62/day |
Skin or skin structure infections | 500 mg | Q8 hours | $10.62/day |
Serious gynecological infections | 2 grams | Q8 hours | $42.45/day |
Intraabdominal infections | 2 grams | Q8 hours | $42.45/day |
Meningitis | 2 grams | Q8 hours | $42.45/day |
Life-threatening infections | 2 grams | Q8 hours | $42.45/day |
Bone and joint infections | 2 grams | Q12 hours | $28.30/day |
Pseudomonas pulmonary infections in cystic fibrosis | 30-50mg/kg | Q8 hours(max,6 grams/day) | |
Mixed infections with Burkholderia cepacia and Pseudomonas aeruginosa | 2 grams | Q8 hours plus cipro | $42.45/day |
Creatinine Clearance | Dose and Frequency |
Crcl 50 to 31 ml/min | 1 gram Q12 hours |
Crcl 30 to 16 ml/min | 1 gram Q24 hours |
Crcl 15 to 6 ml/min | 500 mg Q24 hours |
Crcl <5 ml/min | 500 mg Q48 hours |
Dose | Frequency |
1 gram loading dose | followed by 1 gram after each dialysis |