Normal Dose|Renal Impairment|Hemodialysis
______________________________________________________
| Indication | Dose | Frequency | Cost |
| Pharyngitis and tonsillitis caused by Streptococcus pyogenes | 500 mg | Q24 hours for 10 days | $6.34/day |
| Acute sinusitis | 250-500 mg | Q12 hours for 10 days | $6.22-$12.68/day |
| Secondary infection of acute bronchitis | 500 mg | Q12 hours for 10 days | $12.68/day |
| Acute bacterial exacerbation of chronic bronchitis | 500 mg | Q12 hours for 10 days | $12.68/day |
| Mild-to-moderate uncomplicated skin and skin structure infections | 250-500 mg
500 mg |
Q12 hours
Q24 hours |
$6.22-$12.68/day
$6.34/day |
| Bacterial pneumonia | 250 mg | TID for 14 days | $9.33/day |
| Creatinine Clearance | Dose and Frequency |
| Crcl >30 ml/min | normal dose and frequency |
| Crcl <30 ml/min | 50% reduction in dosage and dosage interval remains unchanged |
| Dose | Frequency |
| 250 mg | to be given following dialysis |