Normal Dose|Renal Impairment|Hemodialysis
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| Indication | Dose | Frequency | Cost |
| Pneumonia | 1 gram | Q6-8 hours | $33.56/day |
| Urinary tract infections | 1 gram | Q6-8 hours | $33.56/day |
| Cutaneous infections | 1 gram | Q6-8 hours | $33.56/day |
| Moderately severe or severe infections | 1 gram
2 grams |
Q4 hours
Q6-8 hours |
$50.34/day
$53.80/day |
| More severe infections or infections requiring higher antibiotic dosage | 2 grams
3 grams |
Q4 hours
Q6 hours |
$80.70/day
$100.68/day |
| Pelvic inflammatory disease | 2 grams | Q6 hours plus doxycycline | $53.80/day |
| Creatinine Clearance | Dose and Frequency |
| Crcl 50-30 ml/min | Loading dose of 1-2 grams followed by 1-2 grams Q8-12 hours |
| Crcl 29-10 ml/min | Loading dose of 1-2 grams followed by 1-2 grams Q12-24 hours |
| Crcl 9-5 ml/min | Loading dose of 1-2 grams followed by 0.5-1 gram Q12-24 hours |
| Crcl <5 ml/min | Loading dose of 1-2 grams fol1owed by 0.5 -1 gram Q24-48 hours |
| Dose | Frequency |
| 1-2 grams | to be given after each dialysis,then patient to receive maintenance doses based upon creatinine clearance |