Normal Dose|Renal Impairment|Hemodialysis
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| Indication | Dose | Frequency | Cost |
| Uncomplicated infections | 1 gram | Q12 hours | $16.00/day |
| Moderate to severe infections | 1-2 grams | Q8 hours | $24-46.75/day |
| Severe infections-septicemia | 2 grams | Q6-8 hours | $62.32/day |
| Life-threatening infections | 2 grams | Q4 hours | $93.48/day |
| Meningitis and other CNS infections | 2 grams | Q6 hours for 7-21 days | $62.32/day |
| Creatinine Clearance | Dose and Frequency |
| Crcl >20 ml/min | usual dosage and dosing interval |
| Crcl <20 ml/min | 1/2 the usual dose at the usual time interval |
| Dose | Frequency |
| 0.5- 2 grams | once daily and a supplemental dose be given after each dialysis period |