Normal Dose|Renal Impairment|Hemodialysis
_____________________________________________________________
| Indication | Dose | Frequency | Cost |
| Intra-abdominal infections including peritonitis | 2 grams
4 grams |
Q12 hours
Q12 hours |
$27.92/day
$55.84/day |
| Urinary tract infections | 2 grams
4 grams |
Q12 hours
Q12 hours |
$27.92/day
$55.84/day |
| Respiratory tract infections | 2 grams
4 grams |
Q12 hours
Q12 hours |
$27.92/day
$55.84/day |
| Skin and skin structure infections | 2 grams
4 grams |
Q12 hours
Q12 hours |
$27.92/day
$55.84/day |
| Severe infections or infections caused by less susceptible organisms | 6-12 grams | Daily given in 2, 3, or 4 equally divided doses | $111.68/day |
| Creatinine Clearance | Dose and Frequency |
| Dosage adjustment is not required | Dosage adjustment is not necessary in renal failure because biliary excretion is the major route of elimination |
| Dose | Frequency |
| Recommended dose | to be scheduled following dialysis since a slight removal of the drug occurs during hemodialysis |