Normal Dose|Renal Impairment|Hemodialysis
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| Indication | Dose | Frequency | Cost |
| Mild to moderate infections | 1 gram | Q24 hours | NA |
| Uncomplicated urinary tract infections | 0.5 gram | Q24 hours | NA |
| Severe or life-threatening infections | 2 grams | Q24 hours | NA |
| Creatinine Clearance | Dose and Frequency | |
| Mild -to-moderate infections | Severe infections | |
| Crcl 79-60 ml/min | 10 mg/kg Q24 hours | 25 mg/kg Q24 hours |
| Crcl 59-40 ml/min | 8 mg/kg Q24 hours | 20 mg/kg Q24 hours |
| Crcl 39-20 ml/min | 4 mg/kg Q24 hours | 15 mg/kg Q24 hours |
| Crcl 19-10 ml/min | 4 mg/kg Q48 hours | 15 mg/kg Q48 hours |
| Crcl 9-5 ml/min | 4 mg/kg Q3 to 5 days | 15 mg/kg Q3 to 5 days |
| Crcl <5 ml/min | 3 mg/kg Q3 to 5 days | 4 mg/kg Q3 to 5 days |
|
Dose and Frequency |
|
Additional doses of cefonicid are not required following dialysis |