Normal Dose|Renal Impairment|Hemodialysis
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Indication | Dose | Frequency | Cost |
Moderate to severe pneumonia | 1-2 grams | Q12 hours for 10 days | $25.20/day |
Febrile neutropenia-empiric therapy | 2 grams | Q8 hours for 7 days or until resolution of neutropenia | $75.60/day |
Mild to moderate uncomplicated or complicated urinary tract infections including pyelonephritis | 0.5-1 gram | Q12 hours for 7-10 days | $25.20/day |
Severe uncomplicated or complicated urinary tract infections including pyelonephritis | 2 grams | Q12 hours for 10 days | $50.40/day |
Moderate to severe uncomplicated skin infections | 2 grams | Q12 hours for 10 days | $50.40/day |
Intra-abdominal infections-complicated | 2 grams | Q12 hours for 7-10 days | $50.40/day |
Creatinine Clearance | 500 mg Q12 hours | 1 gram Q12hours | 2 grams Q12 hours | 2 grams Q8 hours |
Crcl 30-60 ml/min | 500 mg Q24 hours | 1 gram Q24 hours | 2 grams Q24 hours | 2 grams Q12 hours |
Crcl 11-29 ml/min | 500 mg Q24 hours | 500 mg Q24 hours | 1 gram Q24 hours | 2 grams Q24 hours |
Crcl <11 ml/min | 250 mg Q24 hours | 250 mg Q24 hours | 500 mg Q24 hours | 1 gram Q24 hours |
Dose | Frequency |
Repeat dose equivalent to the initial dose | to be given at the end of each dialysis |