CEFEPIME

Normal Dose|Renal Impairment|Hemodialysis

Index

___________________________________________

 

Normal Dose

 

Indication Dose Frequency Cost
Moderate to severe pneumonia 1-2 grams Q12 hours for 10 days $25.20/day
Febrile neutropenia-empiric therapy 2 grams Q8 hours for 7 days or until resolution of neutropenia $75.60/day
Mild to moderate uncomplicated or complicated urinary tract infections including pyelonephritis 0.5-1 gram Q12 hours for 7-10 days $25.20/day
Severe uncomplicated or complicated urinary tract infections including pyelonephritis 2 grams Q12 hours for 10 days $50.40/day
Moderate to severe uncomplicated skin infections 2 grams Q12 hours for 10 days $50.40/day
Intra-abdominal infections-complicated 2 grams Q12 hours for 7-10 days $50.40/day


Renal Impairment

 

Usual dose that would be used if the patient's renal function was normal
Creatinine Clearance 500 mg Q12 hours 1 gram Q12hours 2 grams Q12 hours 2 grams Q8 hours
Crcl 30-60 ml/min 500 mg Q24 hours 1 gram Q24 hours 2 grams Q24 hours 2 grams Q12 hours
Crcl 11-29 ml/min 500 mg Q24 hours 500 mg Q24 hours 1 gram Q24 hours 2 grams Q24 hours
Crcl <11 ml/min 250 mg Q24 hours 250 mg Q24 hours 500 mg Q24 hours 1 gram Q24 hours


Hemodialysis

 

Dose Frequency
Repeat dose equivalent to the initial dose to be given at the end of each dialysis

Top