Normal Dose|Renal Impairment|Hemodialysis
______________________________________________________________
| Indication | Dose | Frequency | Cost |
| Streptococcal pharyngitis and tonsillitis | 300 mg
600 mg |
Q12 hours for 10 days
Q24 hours for 10 days |
$6.58/day
$6.58/day |
| Acute maxillary sinusitis | 300 mg
600 mg |
Q12 hours for 10 days
Q24 hours for 10 days |
$6.58/day
$6.58/day |
| Acute exacerbations of chronic bronchitis | 300 mg
600 mg |
Q12 hours for 10 days
Q24 hours for 10 days |
$6.58/day
$6.58/day |
| Community -acquired pneumonia | 300 mg
600 mg |
Q12 hours for 10 days
Q24 hours for 10 days |
$6.58/day
$6.58/day |
| Uncomplicated skin and skin structure infections | 300 mg | Q12 hours | $6.58/day |
| Creatinine clearance | Dose and Frequency |
| Crcl >30 ml/min | normal dose and dosing interval |
| Crcl <30 ml/min | 300 mg Q24 hours |
| Dose | Frequency |
| 300 mg | to be given at the end of each dialysis and subsequent doses administered every 48 hours |