Normal Dose|Renal Impairment|Hemodialysis
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| Indication | Dose | Frequency | Cost |
| Uncomplicated urinary tract infections | 1 or 2 grams | Q24 hours as a single dose or in 2 equally divided doses | $8.08/day |
| Other urinary tract infections | 1 gram | twice daily | $4.04/day |
| Skin and skin structure infections | 1 gram | Q24 hours as a single dose or in 2 equally divided doses | $4.04/day |
| Pharyngitis and tonsillitis caused by Streptococcus pyogenes ( group A beta-hemolytic streptococci) | 1 gram | Q24 hours as a single dose or in 2 equally divided doses | $4.04/day |
| Creatinine Clearance | Dose and Frequency |
| Crcl 25 to 50 ml/min | Initial loading dose of 1 gram followed by 500 mg Q12 hours |
| Crcl 10 to 25 ml /min | Initial loading dose of 1 gram followed by 500 mg Q24 hours |
| Crcl 0 to 10 ml/min | Initial loading dose of 1 gram followed by 500 mg Q36 hours |
| Dose | Frequency |
| 1 gram | to be given at the end of each session and a further 1 gram Q72 hours |