Normal Dose|Renal Impairment|Hemodialysis
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| Indication | Dose | Frequency | Cost |
| Gram-negative infections | 1-2 grams | Q8-12 hours | $44.82-$89.46/day |
| Urinary tract infections | 500-1 grams | Q8-12 hours | $23.46-$44.82/day |
| Moderately severe systemic infections | 1-2 grams | Q8-12 hours | $44.82-$89.46/day |
| Severe systemic or life-threatening infections, especially infections caused by Pseudomonas aeruginosa | 2 grams | Q6-8 hours | $119.28/day |
| Meningitis | 2 grams | Q6 hours | $119.28/day |
| Cystic fibrosis with pulmonary infections caused by Pseudomonas aeruginosa | 2 grams | Q8 hours | $89.46/day |
| Creatinine Clearance | Dose and Frequency |
| Crcl >30 ml/min | usual dose and dosing interval |
| Crcl 10-30 ml/min | 1-2 grams loading dose followed by maintenance doses equal to one-half the usual dose given at the usual dosing interval |
| Crcl <10 ml/min | 1-2 grams loading dose followed by a maintenance dose equal to one-fourth of the loading dose given at the usual dosing interval |
| Dose | Frequency |
| Loading dose equal to the standard dose | give one-fourth the loading dose at standard dosing intervals. For serious infections , in addition to the maintenance doses, one-eighth of the loading dose, should be given after each dialysis |