AMPICILLIN

Normal Dose|Renal Impairment|Hemodiaylsis

Index

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Normal Dose

 

Indication Dose Frequency Cost
Gastrointestinal-tract infections 500 mg(oral)

500 mg(inj)

Q6 hours

Q6 hours

$1.00/day

$1.80/day

Genitourinary tract infection 500 mg(oral)

500 mg(inj)

Q6 hours

Q6 hours

$1.00/day

$1.80/day

Respiratory tract infections 250 mg(oral)

250 -500 mg(inj)

Q6 hours

Q6 hours

$0.50/day

$1.80/day

Endocarditis(treatment) 3 grams(inj) Q6 hours(12 grams/day) $14.88/day
Pregnant women- Group B Streptococci 2 grams loading dose followed by 1 gram Q4 hours until delivery $2.70/day
Septicemia or bacterial meningitis 8-14 grams given in equally divided doses every 3-4 hours $14.88/day



Renal Impairment

 

Creatinine Clearance Dose and Frequency
Crcl >50 ml/min usual dose Q6 hours
Crcl 10 to 50 ml/min usual dose Q6-12 hours
Crcl <10 ml/min usual dose Q12-16 hours



Hemodialysis

 

Dose and Frequency

Ampicillin is removed by hemodialysis . A maintenance dose is recommended after dialysis


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