Normal Dose |Renal Impairment|Hemodialysis
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| INDICATION | DOSE | FREQUENCY | COST |
| Mild to moderate infections-ear, nose, throat;skin and skin structure; or genitourinary tract | 500mg
250mg |
Q 12 hours
Q 8 hours |
$1.00/day
$1.00/day |
| Severe infections-ear, nose, throat; skin and skin structure; or genitourinary tract | 875mg
500mg |
Q12 hours
Q8 hours |
$1.00/day
$1.00/day |
| Mild, moderate, or severe lower respiratory tract infections | 875mg
500mg |
Q12 hours
Q8 hours |
$1.00/day
$1.00/day |
| CREATININE CLEARANCE | DOSE | FREQUENCY |
| Crcl <10 ml/min | 250 mg or 500 mg | Q24 hours,depending on severity of infection |
| Crcl 10 ml/min to 30 ml/min | 250 mg or 500 mg | Q12 hours, depending on severity of infection |
| Crcl <30 ml/min | should not receive 875 mg tablet |
| DOSE | FREQUENCY |
| 250 mg or 500 mg | Q24 hours ,depending on the severity of the infection. Additional doses should be administered both during and at the end of dialysis |