Normal Dose|Renal Impairment|Hemodialysis
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| Indication | Dose | Frequency | Cost |
| Bacterial infections-usual dose | 15 mg/kg/day | divide dose Q8-12 hours | |
| Uncomplicated urinary tract infections | 250 mg | BID | |
| Pulmonary infections in patients with cystic fibrosis | 5-7.5 mg | Q8 hours |
| Creatinine Clearance | Dose and Frequency |
| Crcl >50 ml/min | 60% to 90% of the normal dose Q12 hours |
| Crcl 10-50 ml/min | 30% to 70% of the dose Q12-18 hours |
| Crcl <10 ml/min | 20% to 30% of the dose Q24-48 hours |
| Dose and Frequency |
| Two-thirds of the normal dose should be given as a supplement after dialysis |