Normal Dose|Renal Impairment|Hemodialysis
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| Indication | Dose | Frequency | Cost |
| Bacterial infections-usual dose | 3.375 grams | Q6 hours | $51.80/day |
| Nosocomial pneumonia-empiric treatment | 3.375 grams | Q4 hours with an aminoglycoside | $77.77/day |
| Serious systemic infections | 12-18 grams/1.5-2.25 grams/day | divide dose Q4-6 hours | $77.77/day |
| Creatinine Clearance | Dose and Frequency |
| Crcl 20-40 ml/min | 2.25 grams Q6 hours |
| Crcl <20 ml/min | 2.25 grams Q8 hours |
| Dose | Frequency |
| 2.25 grams | Q8 hours and a supplemental dose of 0.75 grams should be given following each dialysis |