Normal Dose|Renal Impairment|Hemodialysis
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| Indication | Dose | Frequency | Cost |
| Bacterial infections-usual dose | 250 mg
500 mg |
TID for 10 days
BID for 10 days |
$6.48/day
$6.36/day |
| Severe infections and respiratory tract infections | 500 mg
875 mg |
TID
BID |
$9.54/day
$8.50/day |
| Cystic fibrosis to suppress the growth of S. aureus and H influenzae in the respiratory tract | 250-500 mg | Q8 hours | $6.48-$9.54/day |
| Creatinine Clearance | Dose and Frequency |
| Crcl 10-30 ml/min | 250-500 mg Q12 hours |
| Crcl <10 ml/min | 250 mg or 500 mg Q24 hours |
| Dose | Frequency |
| 250 mg or 500 mg | Q24 hours with a supplemental dose both during and at the end of dialysis |